Derek J. Chadwick

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in…

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, i…

Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in As…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food sur…

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and baso…

Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception,…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are …

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders…

Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with per…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known t…

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channe…

Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions…

Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essen…

Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning sta…

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international …

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…

A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecr…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…

Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses n…

Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…

A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.…

Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to envi…

This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause …

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function …

As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields o…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tu…

The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary f…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…

With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of…

A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to th…