Derek J. Chadwick

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…

This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and baso…

How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in th…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions…

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever…

Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…

A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecr…

Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…

A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.…

Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to envi…

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising …

As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields o…

The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary f…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…

Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic …