Derek J. Chadwick

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause …

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international …

Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to envi…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever…

As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields o…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions…

Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic …

An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tu…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channe…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…

Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…

This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…

The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary f…

How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in th…