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Фармакология

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ADMET for Medicinal Chemists. A Practical Guide
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This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of the…
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Animal Models for Human Cancer. Discovery and Development of Novel Therapeutics
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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for can…
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Neuroprotective Natural Products. Clinical Aspects and Mode of Action
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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an ove…
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Protein-Ligand Interactions
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Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for develop…
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Prescribing Scenarios at a Glance
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Prescribing Scenarios at a Glance is an innovative resource which allows medical students and junior doctors to practise prescribing skills safely for…
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Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies
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Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological …
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Fragment-based Drug Discovery. Lessons and Outlook
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From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often …
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Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry
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This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical produ…
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Nonclinical Safety Assessment. A Guide to International Pharmaceutical Regulations
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Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while ne…
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Quantitative Methods for Health Research. A Practical Interactive Guide to Epidemiology and Statistics
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A practical introduction to epidemiology, biostatistics, and research methodology for the whole health care community This comprehensive text, which h…
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Ethnopharmacology
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Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences res…
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Molecular Pharmacology. From DNA to Drug Discovery
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This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug ta…
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Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery
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Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompass…
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Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges
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The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of t…
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Handbook of Chemical and Biological Plant Analytical Methods, 3 Volume Set
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Plants and plant-derived compounds and drugs are becoming more and more popular with increasing numbers of scientists researching plant analysis. The …
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Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
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This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmaco…
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ABC Transporters and Multidrug Resistance
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A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (AB…
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Reactive Drug Metabolites
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Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the larges…
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Continuous Processing in Pharmaceutical Manufacturing
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With contributions from biotechnologists and bioengineers, this ready reference describes the state of the art in industrial biopharmaceutical product…
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Basic Pharmacokinetics and Pharmacodynamics. An Integrated Textbook and Computer Simulations
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Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and phar…
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Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies
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With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand com…
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Pharmacogenomics of Human Drug Transporters. Clinical Impacts
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Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understandi…
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Targeted Biomarker Quantitation by LC-MS
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The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientis…
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Drug Design of Zinc-Enzyme Inhibitors. Functional, Structural, and Disease Applications
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Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition elemen…
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Biomolecular Simulations in Structure-Based Drug Discovery
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A timely and topical survey of modern simulation tools and their applications in real-life drug discovery, allowing for better and quicker results in …
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Evaluation of Drug Candidates for Preclinical Development. Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
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Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» dru…
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Pediatric Drug Development
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Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly v…
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Scaffold Hopping in Medicinal Chemistry
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This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the…
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Aspartic Acid Proteases as Therapeutic Targets
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In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part pr…
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Polypharmacology in Drug Discovery
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An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, on…
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Physicochemical and Biomimetic Properties in Drug Discovery, Enhanced Edition. Chromatographic Techniques for Lead Optimization
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Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemica…
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Production of Plasma Proteins for Therapeutic Use
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Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading expert…
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Data Mining in Drug Discovery
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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering …
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Drug Bioavailability. Estimation of Solubility, Permeability, Absorption and Bioavailability
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The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated …
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Основы фармакологии / Essentials of Pharmacology
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Учебное пособие представляет собой систематизированную информацию по основным разделам фармакологии: общей фармакологии, нейротропным средствам, средс…
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Biophysical Methods for Biotherapeutics. Discovery and Development Applications
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With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical developme…
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Natural Products Targeting Clinically Relevant Enzymes
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The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products…
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Drug Discovery Toxicology. From Target Assessment to Translational Biomarkers
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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy an…
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Personalizing Precision Medicine. A Global Voyage from Vision to Reality
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The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. Sh…
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Медико-биологическое обеспечение подготовки хоккеистов
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В монографии с точки зрения различий в механизмах энергообеспечения игроков с разным амплуа рассмотрены многогранные метаболические сдвиги в организме…
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Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies
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Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in mo…
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Medicinal Chemistry of Nucleic Acids
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with exper…
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Predictive Toxicology. From Vision to Reality
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Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers al…
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An Introduction to Pharmacovigilance
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Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other dr…
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Спортивная нутрициология
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В книге систематизированы основные классы пищевых добавок и специализированных продуктов питания, предназначенных для улучшения физической и функциона…
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