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Фармакология

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Successful Drug Discovery, Volume 1
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The first volume of the book series «Successful Drug Discovery» is focusing on new drug discoveries during the last decade, from established drugs to …
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Medicinal Chemistry of Nucleic Acids
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with exper…
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Microneedle-mediated Transdermal and Intradermal Drug Delivery
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Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vacc…
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ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins. Applications in Drug Discovery and Development
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With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement tra…
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Translational ADMET for Drug Therapy. Principles, Methods, and Pharmaceutical Applications
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Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, a…
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Phytotherapies. Efficacy, Safety, and Regulation
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Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues. • Helps rea…
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Natural Products Targeting Clinically Relevant Enzymes
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The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products…
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Protein and Peptide Mass Spectrometry in Drug Discovery
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The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical me…
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Oral Formulation Roadmap from Early Drug Discovery to Development
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Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to for…
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Benefit-Risk Appraisal of Medicines. A systematic approach to decision-making
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Benefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately …
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Critical Pathways to Success in CNS Drug Development
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Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors de…
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Production of Plasma Proteins for Therapeutic Use
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Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading expert…
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Successful Drug Discovery, Volume 2
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Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it…
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Fragment-based Drug Discovery. Lessons and Outlook
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From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often …
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Global New Drug Development. An Introduction
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The development of new drugs is very complex, costly and risky. Its success is highly dependent on an intense collaboration and interaction between ma…
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Bioisosteres in Medicinal Chemistry
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Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such…
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Pediatric Drug Development
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Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly v…
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Blood-Brain Barrier in Drug Discovery. Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs
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Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can af…
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Animal Models for Human Cancer. Discovery and Development of Novel Therapeutics
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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for can…
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Advanced Drug Delivery
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Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, pre…
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In vivo Models for Drug Discovery
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This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all m…
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Pharmacogenomics of Human Drug Transporters. Clinical Impacts
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Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understandi…
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Peptide Chemistry and Drug Design
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This book focuses on peptides as drugs, a growing area of pharmaceutical research and development. It helps readers solve problems of discovering, dev…
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Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies
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Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in mo…
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Biophysical Methods for Biotherapeutics. Discovery and Development Applications
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With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical developme…
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Oral Bioavailability Assessment. Basics and Strategies for Drug Discovery and Development
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Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailabi…
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ABC Transporters and Multidrug Resistance
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A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (AB…
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Drug-Membrane Interactions. Analysis, Drug Distribution, Modeling
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Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with th…
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Drug Utilization Research. Methods and Applications
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Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understan…
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Physicochemical and Biomimetic Properties in Drug Discovery, Enhanced Edition. Chromatographic Techniques for Lead Optimization
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Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemica…
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Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery
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Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompass…
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Molecular Pharmacology. From DNA to Drug Discovery
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This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug ta…
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Predictive Approaches in Drug Discovery and Development. Biomarkers and In Vitro / In Vivo Correlations
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Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development a…
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Attrition in the Pharmaceutical Industry. Reasons, Implications, and Pathways Forward
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With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical ind…
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Evaluation of Drug Candidates for Preclinical Development. Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
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Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» dru…
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Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry
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This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical produ…
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Ibuprofen. Discovery, Development and Therapeutics
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Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and in…
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Antibody-Drug Conjugates. Fundamentals, Drug Development, and Clinical Outcomes to Target Cancer
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Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the dru…
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Drug Discovery. Practices, Processes, and Perspectives
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Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leadin…
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Cardiovascular Diseases. From Molecular Pharmacology to Evidence-Based Therapeutics
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Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, …
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Neuroprotective Natural Products. Clinical Aspects and Mode of Action
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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an ove…
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Pharmacokinetics and Metabolism in Drug Design
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In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment…
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General and Molecular Pharmacology. Principles of Drug Action
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With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecul…
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Essential Statistics for the Pharmaceutical Sciences
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Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmac…
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Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies
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With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand com…
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