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Фармакология

Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies
Structure-based Design of Drugs and Other Bioactive Molecules. Tools and Strategies
Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in mo…
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Biophysical Methods for Biotherapeutics. Discovery and Development Applications
Biophysical Methods for Biotherapeutics. Discovery and Development Applications
With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical developme…
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Carbohydrate Recognition. Biological Problems, Methods, and Applications
Carbohydrate Recognition. Biological Problems, Methods, and Applications
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the dev…
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Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders
Vanilloid Receptor TRPV1 in Drug Discovery. Targeting Pain and Other Pathological Disorders
Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain tra…
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Absorption and Drug Development. Solubility, Permeability, and Charge State
Absorption and Drug Development. Solubility, Permeability, and Charge State
Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the cu…
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Drug Utilization Research. Methods and Applications
Drug Utilization Research. Methods and Applications
Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understan…
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Physicochemical and Biomimetic Properties in Drug Discovery, Enhanced Edition. Chromatographic Techniques for Lead Optimization
Physicochemical and Biomimetic Properties in Drug Discovery, Enhanced Edition. Chromatographic Techniques for Lead Optimization
Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemica…
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Peptide Drug Discovery and Development. Translational Research in Academia and Industry
Peptide Drug Discovery and Development. Translational Research in Academia and Industry
Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the «bench to bedside» translati…
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Polypharmacology in Drug Discovery
Polypharmacology in Drug Discovery
An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, on…
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Drug Metabolism Handbook. Concepts and Applications
Drug Metabolism Handbook. Concepts and Applications
A valuable reference tool for professionals involved in the industry, Drug Metabolism in Pharmaceuticals covers new tools such as LC-MS and LC-MS-NMR …
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Attrition in the Pharmaceutical Industry. Reasons, Implications, and Pathways Forward
Attrition in the Pharmaceutical Industry. Reasons, Implications, and Pathways Forward
With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical ind…
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Evaluation of Drug Candidates for Preclinical Development. Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
Evaluation of Drug Candidates for Preclinical Development. Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology
Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» dru…
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Collaborative Innovation in Drug Discovery. Strategies for Public and Private Partnerships
Collaborative Innovation in Drug Discovery. Strategies for Public and Private Partnerships
Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the sky…
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Biopharmaceutical Production Technology, 2 Volume Set
Biopharmaceutical Production Technology, 2 Volume Set
Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to …
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Lead Generation Approaches in Drug Discovery
Lead Generation Approaches in Drug Discovery
An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the …
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Drug Discovery. Practices, Processes, and Perspectives
Drug Discovery. Practices, Processes, and Perspectives
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leadin…
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Cardiovascular Diseases. From Molecular Pharmacology to Evidence-Based Therapeutics
Cardiovascular Diseases. From Molecular Pharmacology to Evidence-Based Therapeutics
Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, …
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Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies
Drug Discrimination. Applications to Medicinal Chemistry and Drug Studies
Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological …
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Development of Therapeutic Agents Handbook
Development of Therapeutic Agents Handbook
A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in cha…
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Systems Biology in Drug Discovery and Development
Systems Biology in Drug Discovery and Development
The first book to focus on comprehensive systems biology as applied to drug discovery and development Drawing on real-life examples, Systems Biology i…
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Essential Statistics for the Pharmaceutical Sciences
Essential Statistics for the Pharmaceutical Sciences
Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmac…
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Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies
Drug Discovery for the Treatment of Addiction. Medicinal Chemistry Strategies
With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand com…
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ADMET for Medicinal Chemists. A Practical Guide
ADMET for Medicinal Chemists. A Practical Guide
This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of the…
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Applications of Microdialysis in Pharmaceutical Science
Applications of Microdialysis in Pharmaceutical Science
Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo …
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Thermodynamics of Pharmaceutical Systems. An introduction to Theory and Applications
Thermodynamics of Pharmaceutical Systems. An introduction to Theory and Applications
Designed for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-nee…
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Translational ADMET for Drug Therapy. Principles, Methods, and Pharmaceutical Applications
Translational ADMET for Drug Therapy. Principles, Methods, and Pharmaceutical Applications
Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, a…
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Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmaco…
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Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice
Stephens' Detection and Evaluation of Adverse Drug Reactions. Principles and Practice
The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not o…
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Metabolic Syndrome. Underlying Mechanisms and Drug Therapies
Metabolic Syndrome. Underlying Mechanisms and Drug Therapies
This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug de…
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Pharmacogenetics and Individualized Therapy
Pharmacogenetics and Individualized Therapy
This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the…
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Benefit-Risk Appraisal of Medicines. A systematic approach to decision-making
Benefit-Risk Appraisal of Medicines. A systematic approach to decision-making
Benefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately …
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Quality of Life. The Assessment, Analysis and Reporting of Patient-reported Outcomes
Quality of Life. The Assessment, Analysis and Reporting of Patient-reported Outcomes
The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition …
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Label-Free Technologies For Drug Discovery
Label-Free Technologies For Drug Discovery
Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be us…
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Genotoxic Impurities. Strategies for Identification and Control
Genotoxic Impurities. Strategies for Identification and Control
This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and …
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Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System. From Biology to Drug Discovery
Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System. From Biology to Drug Discovery
This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert…
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Global New Drug Development. An Introduction
Global New Drug Development. An Introduction
The development of new drugs is very complex, costly and risky. Its success is highly dependent on an intense collaboration and interaction between ma…
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Ethnopharmacology
Ethnopharmacology
Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences res…
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Targets and Emerging Therapies for Schizophrenia
Targets and Emerging Therapies for Schizophrenia
New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schi…
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Detection and Quantification of Antibodies to Biopharmaceuticals. Practical and Applied Considerations
Detection and Quantification of Antibodies to Biopharmaceuticals. Practical and Applied Considerations
The definitive book on the neutralization of recombinant biopharmaceuticals Recombinant biopharmaceuticals are an important tool for treating a range …
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The Hands-on Guide to Clinical Pharmacology
The Hands-on Guide to Clinical Pharmacology
Are you about to sit your pharmacology exams? Do you lack confidence in prescribing? Would it help to have a quick reference, pocket-sized reassurance…
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Advanced Drug Delivery
Advanced Drug Delivery
Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, pre…
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Oral Bioavailability. Basic Principles, Advanced Concepts, and Applications
Oral Bioavailability. Basic Principles, Advanced Concepts, and Applications
Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of …
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Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena
Ligand-Binding Assays. Development, Validation, and Implementation in the Drug Development Arena
A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of…
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Novel Therapeutic Targets for Antiarrhythmic Drugs
Novel Therapeutic Targets for Antiarrhythmic Drugs
Profiles potential treatment approaches for cardiac arrhythmias Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly hal…
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Prescribing at a Glance
Prescribing at a Glance
The principles of drug therapies are fundamental to medical practitioners in all branches; but are often difficult to get to grips with. Prescribing a…
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