Фармакология

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical me…

Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to for…

Benefit-risk assessment is at the centre of the approval process for every new medicine. The ability to assess the risks of a new medicine accurately …

The assessment of patient reported outcomes and health-related quality of life continue to be rapidly evolving areas of research and this new edition …

Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be us…

Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it…

From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often …

The development of new drugs is very complex, costly and risky. Its success is highly dependent on an intense collaboration and interaction between ma…

Ethnopharmacology is one of the world’s fastest-growing scientific disciplines encompassing a diverse range of subjects. It links natural sciences res…

New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schi…

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can af…

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for can…

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, pre…

Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of …

A consolidated and comprehensive reference on ligand-binding assays Ligand-binding assays (LBAs) stand as the cornerstone of support for definition of…

This book focuses on peptides as drugs, a growing area of pharmaceutical research and development. It helps readers solve problems of discovering, dev…

Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in mo…

With a focus on practical applications of biophysical techniques, this book links fundamental biophysics to the process of biopharmaceutical developme…

This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the dev…

Examines the emerging therapeutic role of TRPV1 TRPV1 is considered an integrator of noxious stimuli and therefore may be at a crossroads for pain tra…

Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with th…

Drug Utilization Research (DUR) is an eclectic scientific discipline, integrating descriptive and analytical methods for the quantification, understan…

Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemica…

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the «bench to bedside» translati…

An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, on…

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development a…

With a focus on case studies of R&D programs in a variety of disease areas, the book highlights fundamental productivity issues the pharmaceutical ind…

Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the «right» dru…

Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the sky…

Cost-effective manufacturing of biopharmaceutical products is rapidly gaining in importance, while healthcare systems across the globe are looking to …

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the dru…

Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leadin…

Written in an accessible style and consistent format, the book covers both the fundamentals and advances in the pharmacology of cardiovascular drugs, …

Drug discrimination: a practical guide to its contributions to the invention of new chemical entities and evaluations of new or known pharmacological …

A comprehensive look at current drug discovery and development methods—and the roadmap for the future Providing both understanding and guidance in cha…

With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecul…

Essential Statistics for the Pharmaceutical Sciences is targeted at all those involved in research in pharmacology, pharmacy or other areas of pharmac…

With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand com…

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of the…

Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo …

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement tra…

Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, a…

This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmaco…

The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not o…

This book provides a comprehensive overview of the development of metabolic syndrome, the underlying mechanisms and therapeutic strategies for drug de…