Фармакология

In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part pr…

Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in …

The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of t…

This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications fro…

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical produ…

Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition elemen…

Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their d…

Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while ne…

Tested and proven solutions to the challenges of biological drug product development Biological drug products play a central role in combating human d…

Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an ove…

With contributions from biotechnologists and bioengineers, this ready reference describes the state of the art in industrial biopharmaceutical product…

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by exp…

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for develop…

The first volume of the book series «Successful Drug Discovery» is focusing on new drug discoveries during the last decade, from established drugs to …

Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with exper…

Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier…

By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broa…

Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers al…

Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues. • Helps rea…

The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products…

Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemo…

Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to fi…

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy an…

Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors de…

Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading expert…

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhi…

This second edition of a global bestseller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (Qb…

Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering …

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such…

Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly v…

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by …

Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs…

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the…

This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all m…

Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understandi…

By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critica…

As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the i…

The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientis…

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailabi…

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (AB…

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integ…

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than …

Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the larges…

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompass…

This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug ta…