Hugo Kubinyi

Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, includin…

Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry. This observation is the basic pa…

The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wuthrich. Edited b…

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and…

As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chem…

In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing a…

Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research. In recent years, various…

This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of…

With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important bi…

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by …

Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation algorithms …

Edited by two experts working at the pioneering pharmaceutical company and major global player in hormone-derived drugs, this handbook and reference s…

The peroral application (swallowing) of a medicine means that the body must first resorb the active substance before it can begin to take effect. The …

In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and st…

By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critica…

This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug devel…

Recent progress in high-throughput screening, combinatorial chemistry and molecular biology has radically changed the approach to drug discovery in th…

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life …

The number-one reference on the topic now contains a wealth of new data: The entire relevant literature over the past six years has been painstakingly…

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integ…

This handbook provides the first-ever inside view of today's integrated approach to rational drug design. Chemoinformatics experts from large pharmace…

The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the…

Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, inc…

The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated …

Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in …

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimin…

From skillful handling of the wide range of technologies to successful applications in drug discovery – this handbook has all the information professi…

When trying to find new methods and problem-solving strategies for their research, scientists often turn to nature for inspiration. An excellent examp…

Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost d…

The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by exp…

Written by experienced experts in molecular modeling, this books describes the basics to the extent that is necessary if one wants to be able to relia…

The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new ch…

The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structure…

In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part pr…

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than …

This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as…

This unique reference source, edited by the world's most respected expert on molecular interaction field software, covers all relevant principles of t…

In keeping with the outstanding importance of lipophilicity in biosciences, this volume examines all its facets in more than twenty contributions from…

Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemo…

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for develop…

This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from gen…

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and…

This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previ…

Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhi…

Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers al…