Hugo Kubinyi
Жанры и тэги:
Data Mining in Drug Discovery
Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering …
ПодробнееAnimal Models for Human Cancer. Discovery and Development of Novel Therapeutics
Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for can…
ПодробнееScaffold Hopping in Medicinal Chemistry
This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the…
ПодробнееReactive Drug Metabolites
Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the larges…
ПодробнееThermodynamics and Kinetics of Drug Binding
This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications fro…
ПодробнееBioisosteres in Medicinal Chemistry
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such…
ПодробнееIn vivo Models for Drug Discovery
This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all m…
ПодробнееPharmacokinetics and Metabolism in Drug Design
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment…
ПодробнееDrug-Membrane Interactions. Analysis, Drug Distribution, Modeling
Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with th…
ПодробнееFragment-based Drug Discovery. Lessons and Outlook
From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often …
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