Derek J. Chadwick

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…

Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with per…

Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning sta…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause …

This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…

Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…

Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control ci…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, ext…

This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…

A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.…

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channe…

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases …

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recent…

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, i…

Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses n…

Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together mu…

Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…

Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known t…

Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coor…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising …

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in…

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international …

Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tu…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…

Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use o…

This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are …

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception,…

The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into…

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…