Derek J. Chadwick

Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many o…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning sta…

The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food sur…

The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuse…

Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use o…

This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function …

Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control ci…

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channe…

Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the…

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of…

Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses n…

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in…

ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…

Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation…

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, i…

Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases …

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to th…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…

Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are …

The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…

Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …

Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception,…

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recent…

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…

Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with per…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, ext…

Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…

Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…

Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essen…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together mu…

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…

Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in As…

The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into…

Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coor…

The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising …