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Derek J. Chadwick

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Gramicidin and Related Ion Channel-Forming Peptides
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Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …
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Somatostatin and Its Receptors
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This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…
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Bioactive Compounds from Plants
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Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to envi…
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Development of the Cardiac Conduction System
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The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause …
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Mammalian TRP Channels as Molecular Targets
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This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…
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The Molecular Biology and Pathology of Elastic Tissues
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Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…
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Percept, Decision, Action
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Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception,…
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P2 Purinoceptors
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Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions…
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Neuronal and Cognitive Effects of Oestrogens
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Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, ext…
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The Biosynthesis of the Tetrapyrrole Pigments
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Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the…
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Neural Transplantation in Neurodegenerative Disease
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The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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Inflammatory Bowel Disease
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Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with per…
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Mechanisms and Biological Significance of Pulsatile Hormone Secretion
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This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…
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Neural Transplantation in Neurodegenerative Disease
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The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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Host-Guest Molecular Interactions
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Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation…
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Antibiotic Resistance
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Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use o…
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The hERG Cardiac Potassium Channel
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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function …
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T Cell Subsets in Infectious and Autoimmune Diseases
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T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…
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Corticotropin-Releasing Factor
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Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coor…
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Oligonucleotides as Therapeutic Agents
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The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…
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Gramicidin and Related Ion Channel-Forming Peptides
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Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …
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Epithelial Anion Transport in Health and Disease
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Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recent…
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Human Genetic Information
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As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields o…
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The Origins and Consequences of Obesity
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This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international …
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Telomeres and Telomerase
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Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essen…
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Insect-Plant Interactions and Induced Plant Defence
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Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…
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The Molecular Basis of Smell and Taste Transduction
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Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…
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Vaccines Against Virally Induced Cancers
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An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tu…
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Purinergic Signalling in Neuron-Glia Interactions
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…
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Cancer and Inflammation
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Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…
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Molecular Clocks and Light Signalling
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The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary f…
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The Biology of Extracellular Molecular Chaperones
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The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…
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Alcohol and Cardiovascular Disease
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Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together mu…
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Purinergic Signalling in Neuron-Glia Interactions
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…
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Rice Biotechnology
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Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in As…
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The Molecular Biology and Pathology of Elastic Tissues
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Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…
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The Biology of Extracellular Molecular Chaperones
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The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…
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Crop Protection and Sustainable Agriculture
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The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food sur…
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Signalling Pathways in Acute Oxygen Sensing
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Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…
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Secondary Metabolites
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A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.…
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Ethnobotany and the Search for New Drugs
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A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to th…
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Circadian Clocks and Their Adjustment
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Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control ci…
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Role of the Sarcoplasmic Reticulum in Smooth Muscle
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Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…
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Nuclear Organization in Development and Disease
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This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…
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Mechanisms and Biological Significance of Pulsatile Hormone Secretion
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This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…
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