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Фармакология

Process Scale Purification of Antibodies
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Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier…
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Novel Antimicrobial Agents and Strategies
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By integrating knowledge from pharmacology, microbiology, molecular medicine, and engineering, researchers from Europe, the U.S. and Asia cover a broa…
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Predictive Toxicology. From Vision to Reality
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Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers al…
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Phytotherapies. Efficacy, Safety, and Regulation
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Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues. • Helps rea…
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Natural Products Targeting Clinically Relevant Enzymes
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The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products…
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Chemokine Receptors as Drug Targets
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Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemo…
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Analogue-based Drug Discovery III
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Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to fi…
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Drug Discovery Toxicology. From Target Assessment to Translational Biomarkers
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As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy an…
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Critical Pathways to Success in CNS Drug Development
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Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors de…
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Production of Plasma Proteins for Therapeutic Use
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Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading expert…
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Phosphodiesterases and Their Inhibitors
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Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhi…
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Method Validation in Pharmaceutical Analysis. A Guide to Best Practice
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This second edition of a global bestseller has been completely redesigned and extensively rewritten to take into account the new Quality by Design (Qb…
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Data Mining in Drug Discovery
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Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering …
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Bioisosteres in Medicinal Chemistry
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Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such…
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Pediatric Drug Development
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Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly v…
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Protein-Protein Interactions in Drug Discovery
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Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by …
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De novo Molecular Design
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Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs…
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Scaffold Hopping in Medicinal Chemistry
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This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the…
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In vivo Models for Drug Discovery
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This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all m…
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Pharmacogenomics of Human Drug Transporters. Clinical Impacts
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Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understandi…
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Antiviral Drug Strategies
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By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critica…
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Transporters as Drug Targets
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As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the i…
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Targeted Biomarker Quantitation by LC-MS
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The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientis…
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Oral Bioavailability Assessment. Basics and Strategies for Drug Discovery and Development
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Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailabi…
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ABC Transporters and Multidrug Resistance
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A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (AB…
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Prodrugs and Targeted Delivery. Towards Better ADME Properties
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This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integ…
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Drug Metabolism Prediction
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The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than …
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Reactive Drug Metabolites
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Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the larges…
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Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery
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Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompass…
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Molecular Pharmacology. From DNA to Drug Discovery
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This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug ta…
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Virtual Screening. Principles, Challenges, and Practical Guidelines
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Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in …
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Fusion Protein Technologies for Biopharmaceuticals. Applications and Challenges
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The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of t…
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Thermodynamics and Kinetics of Drug Binding
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This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications fro…
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Pharmaceutical Excipients. Properties, Functionality, and Applications in Research and Industry
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This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical produ…
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Ibuprofen. Discovery, Development and Therapeutics
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Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and in…
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Antibiotics. Targets, Mechanisms and Resistance
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Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their d…
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Nonclinical Safety Assessment. A Guide to International Pharmaceutical Regulations
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Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while ne…
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Biological Drug Products. Development and Strategies
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Tested and proven solutions to the challenges of biological drug product development Biological drug products play a central role in combating human d…
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Neuroprotective Natural Products. Clinical Aspects and Mode of Action
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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an ove…
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Pharmacokinetics and Metabolism in Drug Design
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In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment…
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Natural Products in Medicinal Chemistry
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The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by exp…
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Protein-Ligand Interactions
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Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for develop…
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Successful Drug Discovery, Volume 1
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The first volume of the book series «Successful Drug Discovery» is focusing on new drug discoveries during the last decade, from established drugs to …
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Medicinal Chemistry of Nucleic Acids
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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with exper…
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Microneedle-mediated Transdermal and Intradermal Drug Delivery
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Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vacc…
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