Фармакология

Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs…

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the…

This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all m…

Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understandi…

This book focuses on peptides as drugs, a growing area of pharmaceutical research and development. It helps readers solve problems of discovering, dev…

As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the i…

The first book to offer a blueprint for overcoming the challenges to successfully quantifying biomarkers in living organisms The demand among scientis…

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailabi…

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (AB…

Barrier, reservoir, target site – those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with th…

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than …

Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the larges…

Here, front-line researchers in the booming field of nanobiotechnology describe the most promising approaches for bioinspired drug delivery, encompass…

This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug ta…

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development a…

The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs—with Enbrel® being one of t…

This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications fro…

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical produ…

Ibuprofen has become one of the foremost pain-relieving medications world-wide with its proven safety and efficacy in a wide variety of painful and in…

Providing practical and proven solutions for antibody-drug conjugate (ADC) drug discovery success in oncology, this book helps readers improve the dru…

Bringing a new drug to market is a costly time-consuming process. Increased regional and international regulation over the last twenty years, while ne…

Tested and proven solutions to the challenges of biological drug product development Biological drug products play a central role in combating human d…

Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an ove…

In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment…

With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecul…

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for develop…

The first volume of the book series «Successful Drug Discovery» is focusing on new drug discoveries during the last decade, from established drugs to …

Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with exper…

Microneedles can be used for delivery of a wide range of drug substances for practically any medical condition and present a real opportunity for vacc…

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement tra…

Tailored to the needs of scientists developing drugs, chemicals, cosmetics and other products this one-stop reference for medicinal chemists covers al…

Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues. • Helps rea…

The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products…

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical me…

Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to for…

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy an…

Covering the latest advances in CNS drug development, this book will guide all those involved in pre-clinical to early clinical trials. The authors de…

Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading expert…

Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it…

From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often …

Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering …

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such…

Most medicines have never been adequately tested for safety and efficacy in pediatric populations and preterm, infants and children are particularly v…

Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can af…

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for can…