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Derek J. Chadwick

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Antibiotic Resistance
Antibiotic Resistance
Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use o…
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Epithelial Anion Transport in Health and Disease
Epithelial Anion Transport in Health and Disease
Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recent…
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Bacterial Responses to pH
Bacterial Responses to pH
Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are …
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Neuronal and Cognitive Effects of Oestrogens
Neuronal and Cognitive Effects of Oestrogens
Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, ext…
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Alcohol and Cardiovascular Disease
Alcohol and Cardiovascular Disease
Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together mu…
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Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …
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The Molecular Basis of Smell and Taste Transduction
The Molecular Basis of Smell and Taste Transduction
Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…
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Corticotropin-Releasing Factor
Corticotropin-Releasing Factor
Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coor…
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Role of the Sarcoplasmic Reticulum in Smooth Muscle
Role of the Sarcoplasmic Reticulum in Smooth Muscle
Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…
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Catalytic Antibodies
Catalytic Antibodies
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic …
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Purinergic Signalling in Neuron-Glia Interactions
Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…
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Variation in the Human Genome
Variation in the Human Genome
The mapping of human genes is proceeding rapidly. Genes associated with specific inherited diseases are being identified, often providing insight into…
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Ethnobotany and the Search for New Drugs
Ethnobotany and the Search for New Drugs
A compilation of articles by prominent experts in their respective fields on compensation for and collaboration with indigenous people in regard to th…
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Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…
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Neural Transplantation in Neurodegenerative Disease
Neural Transplantation in Neurodegenerative Disease
The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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The Biosynthesis of the Tetrapyrrole Pigments
The Biosynthesis of the Tetrapyrrole Pigments
Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the…
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Circadian Clocks and Their Adjustment
Circadian Clocks and Their Adjustment
Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control ci…
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Growth Factors and Psychiatric Disorders
Growth Factors and Psychiatric Disorders
The recent identification of susceptibility genes for schizophrenia, depression and learning and memory dysfunction suggest that psychiatric disorders…
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Dental Enamel
Dental Enamel
The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuse…
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P2 Purinoceptors
P2 Purinoceptors
Many different pathological conditions are currently under investigation as therapeutic targets of purines including cancer, cardiovascular conditions…
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The Molecular Biology and Pathology of Elastic Tissues
The Molecular Biology and Pathology of Elastic Tissues
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…
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Crop Protection and Sustainable Agriculture
Crop Protection and Sustainable Agriculture
The increase in the world population and changes in welfare have led to an enormously expanding demand for food. In the industrialized world, food sur…
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Exploring Brain Functional Anatomy with Positron Tomography
Exploring Brain Functional Anatomy with Positron Tomography
Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…
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The hERG Cardiac Potassium Channel
The hERG Cardiac Potassium Channel
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function …
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Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin and Related Ion Channel-Forming Peptides
Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since …
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Host-Guest Molecular Interactions
Host-Guest Molecular Interactions
Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation…
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IgE, Mast Cells and the Allergic Response
IgE, Mast Cells and the Allergic Response
Reviews recent basic research into IgE, mast cells, and the allergic response and the relevance of this work to human pathophysiology, and discusses n…
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Percept, Decision, Action
Percept, Decision, Action
Seemingly simple behaviours turn out, on reflection, to be discouragingly complex. For many years, cognitive operations such as sensation, perception,…
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Mitochondrial Biology
Mitochondrial Biology
With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of…
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Purinergic Signalling in Neuron-Glia Interactions
Purinergic Signalling in Neuron-Glia Interactions
ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…
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Innate Immunity to Pulmonary Infection
Innate Immunity to Pulmonary Infection
Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases …
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Steroids and Neuronal Activity
Steroids and Neuronal Activity
Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many o…
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Rice Biotechnology
Rice Biotechnology
Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in As…
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Postimplantation Development in the Mouse
Postimplantation Development in the Mouse
Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning sta…
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Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence
Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…
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Mechanisms and Biological Significance of Pulsatile Hormone Secretion
Mechanisms and Biological Significance of Pulsatile Hormone Secretion
This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…
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The Biology of Extracellular Molecular Chaperones
The Biology of Extracellular Molecular Chaperones
The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…
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Inflammatory Bowel Disease
Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with per…
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Neural Transplantation in Neurodegenerative Disease
Neural Transplantation in Neurodegenerative Disease
The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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Molecular Clocks and Light Signalling
Molecular Clocks and Light Signalling
The ability at the molecular level to keep track of time is a property shared by organisms ranging from the simplest unicells to humans. The primary f…
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T Cell Subsets in Infectious and Autoimmune Diseases
T Cell Subsets in Infectious and Autoimmune Diseases
T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…
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Vascular Development
Vascular Development
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, i…
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Telomeres and Telomerase
Telomeres and Telomerase
Telomeres and Telomerase Chairman: Sydney Brenner, 1997 Telomeres are the protective genetic elements located at the ends of chromosomes and are essen…
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Exploring Brain Functional Anatomy with Positron Tomography
Exploring Brain Functional Anatomy with Positron Tomography
Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…
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Somatostatin and Its Receptors
Somatostatin and Its Receptors
This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signa…
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