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Derek J. Chadwick

Mast Cells and Basophils
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The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and baso…
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Exploring Brain Functional Anatomy with Positron Tomography
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Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET…
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The hERG Cardiac Potassium Channel
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This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function …
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Steroids and Neuronal Activity
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Classical studies of steroid hormones are concerned with their regulation of protein synthesis via the modulation of genomic transcription. But many o…
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The Rising Trends in Asthma
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Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising …
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Alcohol and Cardiovascular Disease
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Both timely and topical, this book examines the most important aspects of the relationship between alcohol consumption and health. Drawing together mu…
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Mitochondrial Biology
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With the recent renaissance in mitochondrial biology and increasing recognition of their role in many diseases, this book provides a timely summary of…
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The Biology of Extracellular Molecular Chaperones
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The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…
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Antibiotic Resistance
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Antibiotic Resistance: Origins, Evolution, Selection and Spread Chairman: Stuart B. Levy, 1997 Over the last 50 years, the rapid increase in the use o…
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Oligonucleotides as Therapeutic Agents
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The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…
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Nuclear Organization in Development and Disease
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This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…
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Purinergic Signalling in Neuron-Glia Interactions
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ATP, the intracellular energy source, is also an extremely important cell–cell signalling molecule for a wide variety of cells across evolutionarily d…
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Role of the Sarcoplasmic Reticulum in Smooth Muscle
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Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…
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Role of the Sarcoplasmic Reticulum in Smooth Muscle
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Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…
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The Biosynthesis of the Tetrapyrrole Pigments
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Prestigious contributors summarize current knowledge regarding the biosynthesis of tetrapyrrole pigments–chlorophyll, haem, vitamin B12. Describes the…
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Osteoarthritic Joint Pain
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Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever…
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Bacterial Responses to pH
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Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are …
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Protein Conformation
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How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in th…
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Neuronal and Cognitive Effects of Oestrogens
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Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, ext…
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Epigenetics
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Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…
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Functional Anatomy of the Neuroendocrine Hypothalamus
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Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…
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Innate Immunity to Pulmonary Infection
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Part of the prestigious Novartis Foundation series, this volume uniquely addresses the use of innate immunity to treat or prevent infectious diseases …
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Postimplantation Development in the Mouse
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Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning sta…
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Insect-Plant Interactions and Induced Plant Defence
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Insect-Plant Interactions and Induced Plant Defence Chair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to de…
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Catalytic Antibodies
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Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic …
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Neural Transplantation in Neurodegenerative Disease
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The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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Dental Enamel
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The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuse…
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Neural Transplantation in Neurodegenerative Disease
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The field of neural transplantation is at a crucial stage, with important clinical trials on transplantation in patients with Parkinson's disease near…
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