Derek J. Chadwick

Chronic inflammation predisposes to some forms of cancer and the host response to malignant disease shows several parallels with inflammation and woun…

A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms.…

Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in…

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to s…

The heat shock, or cell stress, response was first identified in the polytene chromosomes of Drosophila. This was later related to the appearance of n…

This book brings together contributions from key investigators in the area of pathological pain. It covers the molecular basis of receptors and channe…

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause …

A number of chronic respiratory diseases including chronic bronchitis, asthma, cystic fibrosis and bronchiectasis are characterized by mucus hypersecr…

This exciting book brings together an international and interdisciplinary group of experts to discuss the importance of pulsatile signalling in the in…

Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effe…

Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to envi…

Recent application of the techniques of molecular biology and patch-clamp physiology has led to rapid advances in understanding the molecular events i…

As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields o…

This volume examines obesity disorders which can lead to diabetes, hypertension and hyperlipidaemia. It offers an interdisciplinary and international …

Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and patholog…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents u…

Asthma is a growing health problem throughout the developed world. This volume presents a critical review of all the possible factors for this rising …

How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in th…

Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known t…

This book draws together contributions from cell and developmental biologists, structural biologists, geneticists and clinical scientists aimed at a b…

Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into…

An interdisciplinary and multinational group of specialists present contributions describing the current status of vaccines against virally induced tu…

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and baso…

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery…

This book brings together contributions from key investigators in the area of Transient Receptor Potential (TRP) channel structure and function. It co…

Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs an…

Osteoarthritis is a chronic degenerative disease associated with joint pain and loss of joint function. It has an estimated incidence of 4 out of ever…